You know your body better than anyone else does -
even your doctor.
I was recently reminded why this is so important.
My endocrinologist and I have been working on getting my hormones to what she considers to be optimal levels. Testosterone was easy; my body never wanted to produce it in the first place and my levels were low (even for a woman) after only a few months of therapy.
Estrogen has been a little bit stickier. Taking the maximum safe dose of oral estradiol, my levels are still about 40% lower than what she'd like. Because of that, at our last visit we decided to try switching from oral delivery to a transdermal patch. On paper it seemed like a perfect idea; the patch is a more reliable delivery method and (theoretically) has fewer side effects.
So I switched. And in a couple of days I was feeling like absolute crap. Anxiety, restlessness, fatigue, progressing to full-on depression - inside a week I was feeling like I had before I'd started hormone replacement. A lot of the physical symptoms of transition were fading, too (I won't get into details there, but trust me).